Heparan Sulfate Mimetics in Cancer Therapy: The Challenge to Define Structural Determinants and the Relevance of Targets for Optimal Activity

Beyond anticoagulation, the therapeutic potential of heparin derivatives and heparan sulfate (HS) mimetics (functionally defined HS mimetics) in oncology is related to their ability to bind and modulate the function of a vast array of HS-binding proteins with pivotal roles in cancer growth and progr...

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Detalles Bibliográficos
Autores principales: Lanzi, Cinzia, Cassinelli, Giuliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278363/
https://www.ncbi.nlm.nih.gov/pubmed/30413079
http://dx.doi.org/10.3390/molecules23112915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278363/
https://www.ncbi.nlm.nih.gov/pubmed/30413079
http://dx.doi.org/10.3390/molecules23112915

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