Molecular Modeling and In Vitro Studies of a Neutral Oxime as a Potential Reactivator for Acetylcholinesterase Inhibited by Paraoxon

The present work aimed to compare the small, neutral and monoaromatic oxime, isatin-3-oxime (isatin-O), to the commercial ones, pralidoxime (2-PAM) and obidoxime, in a search for a new potential reactivator for acetylcholinesterase (AChE) inhibited by the pesticide paraoxon (AChE/POX) as well as a n...

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Detalles Bibliográficos
Autores principales: de Paula, Reuel L., de Almeida, Joyce S. F. D., Cavalcante, Samir F. A., Gonçalves, Arlan S., Simas, Alessandro B. C., Franca, Tanos C. C., Valis, Martin, Kuca, Kamil, Nepovimova, Eugenie, Granjeiro, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278417/
https://www.ncbi.nlm.nih.gov/pubmed/30424582
http://dx.doi.org/10.3390/molecules23112954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278417/
https://www.ncbi.nlm.nih.gov/pubmed/30424582
http://dx.doi.org/10.3390/molecules23112954

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