Molecular Modeling and Design Studies of Purine Derivatives as Novel CDK2 Inhibitors

Cyclin-dependent kinase 2 (CDK2) is a potential target for treating cancer. Purine heterocycles have attracted particular attention as the scaffolds for the development of CDK2 inhibitors. To explore the interaction mechanism and the structure–activity relationship (SAR) and to design novel candidat...

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Detalles Bibliográficos
Autores principales: Zhang, Gaomin, Ren, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278423/
https://www.ncbi.nlm.nih.gov/pubmed/30423939
http://dx.doi.org/10.3390/molecules23112924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278423/
https://www.ncbi.nlm.nih.gov/pubmed/30423939
http://dx.doi.org/10.3390/molecules23112924

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