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Small Molecule Inhibitors of HSF1-Activated Pathways as Potential Next-Generation Anticancer Therapeutics

Targeted therapy is an emerging paradigm in the development of next-generation anticancer drugs. Heat shock factor 1 (HSF1) has been identified as a promising drug target because it regulates several pathways responsible for cancer cell growth, metastasis, and survival. Studies have clearly demonstr...

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Detalles Bibliográficos
Autores principales: Sharma, Chiranjeev, Seo, Young Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278446/
https://www.ncbi.nlm.nih.gov/pubmed/30356024
http://dx.doi.org/10.3390/molecules23112757