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The Two Isoforms of Lyn Display Different Intramolecular Fuzzy Complexes with the SH3 Domain

The function of the intrinsically disordered Unique domain of the Src family of tyrosine kinases (SFK), where the largest differences between family members are concentrated, remains poorly understood. Recent studies in c-Src have demonstrated that the Unique region forms transient interactions, des...

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Detalles Bibliográficos
Autores principales: Teixeira, João M. C., Fuentes, Héctor, Bielskutė, Stasė, Gairi, Margarida, Żerko, Szymon, Koźmiński, Wiktor, Pons, Miquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278449/
https://www.ncbi.nlm.nih.gov/pubmed/30360468
http://dx.doi.org/10.3390/molecules23112731