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The Two Isoforms of Lyn Display Different Intramolecular Fuzzy Complexes with the SH3 Domain
The function of the intrinsically disordered Unique domain of the Src family of tyrosine kinases (SFK), where the largest differences between family members are concentrated, remains poorly understood. Recent studies in c-Src have demonstrated that the Unique region forms transient interactions, des...
Autores principales: | Teixeira, João M. C., Fuentes, Héctor, Bielskutė, Stasė, Gairi, Margarida, Żerko, Szymon, Koźmiński, Wiktor, Pons, Miquel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278449/ https://www.ncbi.nlm.nih.gov/pubmed/30360468 http://dx.doi.org/10.3390/molecules23112731 |
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