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Towards a Stochastic Paradigm: From Fuzzy Ensembles to Cellular Functions
The deterministic sequence → structure → function relationship is not applicable to describe how proteins dynamically adapt to different cellular conditions. A stochastic model is required to capture functional promiscuity, redundant sequence motifs, dynamic interactions, or conformational heterogen...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278454/ https://www.ncbi.nlm.nih.gov/pubmed/30453632 http://dx.doi.org/10.3390/molecules23113008 |