HSP70 Acetylation Prevents Combined mTORC1/2 Inhibitor and Curcumin Treatment-Induced Apoptosis

We previously reported that PP242 (dual inhibitor of mTORC1/2) plus curcumin induced apoptotic cell death through lysosomal membrane permeabilization (LMP)-mediated autophagy. However, the relationship between ER stress and apoptotic cell death by combined PP242 and curcumin treatment remains unknow...

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Detalles Bibliográficos
Autores principales: Seo, Seung Un, Min, Kyoung-jin, Woo, Seon Min, Seo, Ji Hae, Kwon, Taeg Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278488/
https://www.ncbi.nlm.nih.gov/pubmed/30356017
http://dx.doi.org/10.3390/molecules23112755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278488/
https://www.ncbi.nlm.nih.gov/pubmed/30356017
http://dx.doi.org/10.3390/molecules23112755

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