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HSP70 Acetylation Prevents Combined mTORC1/2 Inhibitor and Curcumin Treatment-Induced Apoptosis

We previously reported that PP242 (dual inhibitor of mTORC1/2) plus curcumin induced apoptotic cell death through lysosomal membrane permeabilization (LMP)-mediated autophagy. However, the relationship between ER stress and apoptotic cell death by combined PP242 and curcumin treatment remains unknow...

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Detalles Bibliográficos
Autores principales:	Seo, Seung Un, Min, Kyoung-jin, Woo, Seon Min, Seo, Ji Hae, Kwon, Taeg Kyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278488/ https://www.ncbi.nlm.nih.gov/pubmed/30356017 http://dx.doi.org/10.3390/molecules23112755

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