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Synthesis of Novel Benzazole Derivatives and Evaluation of Their Antidepressant-Like Activities with Possible Underlying Mechanisms

Novel benzazole derivative compounds 4a–4h were obtained by the reaction of corresponding 2-(benzazol-2-ylthio)acetohydrazide and appropriate 4-substituted benzaldehydes. The chemical structures of the synthesized compounds were elucidated by FT-IR, (1)H-NMR, (13)C-NMR and LCMS spectroscopic methods...

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Detalles Bibliográficos
Autores principales: Tokgöz, Gamze, Demir Özkay, Ümide, Osmaniye, Derya, Turan Yücel, Nazlı, Can, Özgür Devrim, Kaplancıklı, Zafer Asım
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278502/
https://www.ncbi.nlm.nih.gov/pubmed/30400609
http://dx.doi.org/10.3390/molecules23112881