Panax notoginseng Saponins Protect Cerebral Microvascular Endothelial Cells against Oxygen-Glucose Deprivation/Reperfusion-Induced Barrier Dysfunction via Activation of PI3K/Akt/Nrf2 Antioxidant Signaling Pathway

Oxidative stress plays a critical role in cerebral ischemia/reperfusion (I/R)-induced blood-brain barrier (BBB) disruption. Panax notoginseng saponins (PNS) possess efficient antioxidant activity and have been used in the treatment of cerebral ischemic stroke in China. In this study, we determined t...

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Detalles Bibliográficos
Autores principales: Hu, Shaonan, Wu, Yali, Zhao, Bo, Hu, Haiyan, Zhu, Baochen, Sun, Zongxi, Li, Pengyue, Du, Shouying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278530/
https://www.ncbi.nlm.nih.gov/pubmed/30373188
http://dx.doi.org/10.3390/molecules23112781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278530/
https://www.ncbi.nlm.nih.gov/pubmed/30373188
http://dx.doi.org/10.3390/molecules23112781

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