A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice

We developed a bacterial expression system to produce a recombinant disintegrin, vicrostatin (VCN), whose structure is based on a natural disintegrin isolated from southern copperhead snake venom. Our goal is to develop VCN for potential clinical translation as an anti-cancer agent. VCN is a peptide...

Descripción completa

Detalles Bibliográficos
Autores principales: Swenson, Steve, Minea, Radu O., Tuan, Cao Duc, Thein, Thu-Zan, Chen, Thomas C., Markland, Francis S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278533/
https://www.ncbi.nlm.nih.gov/pubmed/30413113
http://dx.doi.org/10.3390/molecules23112918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278533/
https://www.ncbi.nlm.nih.gov/pubmed/30413113
http://dx.doi.org/10.3390/molecules23112918

Ejemplares similares