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A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice
We developed a bacterial expression system to produce a recombinant disintegrin, vicrostatin (VCN), whose structure is based on a natural disintegrin isolated from southern copperhead snake venom. Our goal is to develop VCN for potential clinical translation as an anti-cancer agent. VCN is a peptide...
Autores principales: | Swenson, Steve, Minea, Radu O., Tuan, Cao Duc, Thein, Thu-Zan, Chen, Thomas C., Markland, Francis S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278533/ https://www.ncbi.nlm.nih.gov/pubmed/30413113 http://dx.doi.org/10.3390/molecules23112918 |
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