Pseudoginsengenin DQ Exhibits Therapeutic Effects in Cisplatin-Induced Acute Kidney Injury via Sirt1/NF-κB and Caspase Signaling Pathway without Compromising Its Antitumor Activity in Mice

In this study, the protective effects of pseudoginsengenin DQ (PDQ) on cisplatin (CDDP)-induced nephrotoxicity were assessed, with a primary investigation into the mechanisms involved. Our results showed that pretreatment with PDQ remarkably restored levels of blood urea nitrogen (BUN) and creatinin...

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Detalles Bibliográficos
Autores principales: Qi, Zeng, Li, Zhuo, Li, Wei, Liu, Yunhe, Wang, Cuizhu, Lin, Hongqiang, Liu, Jinping, Li, Pingya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278544/
https://www.ncbi.nlm.nih.gov/pubmed/30469321
http://dx.doi.org/10.3390/molecules23113038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278544/
https://www.ncbi.nlm.nih.gov/pubmed/30469321
http://dx.doi.org/10.3390/molecules23113038

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