An Accurate and Effective Method for Measuring Osimertinib by UPLC-TOF-MS and Its Pharmacokinetic Study in Rats

Osimertinib, a new-generation inhibitor of the epidermal growth factor, has been used for the clinical treatment of advanced T790M mutation-positive tumors. In this research, an original analysis method was established for the quantification of osimertinib by ultra-performance liquid chromatography...

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Detalles Bibliográficos
Autores principales: Dong, Song-Tao, Li, Ying, Yang, Hao-Tian, Wu, Yin, Li, Ya-Jing, Ding, Cong-Yang, Meng, Lu, Dong, Zhan-Jun, Zhang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278556/
https://www.ncbi.nlm.nih.gov/pubmed/30404182
http://dx.doi.org/10.3390/molecules23112894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278556/
https://www.ncbi.nlm.nih.gov/pubmed/30404182
http://dx.doi.org/10.3390/molecules23112894

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