Heteroatom Substitution at Amide Nitrogen—Resonance Reduction and HERON Reactions of Anomeric Amides

This review describes how resonance in amides is greatly affected upon substitution at nitrogen by two electronegative atoms. Nitrogen becomes strongly pyramidal and resonance stabilisation, evaluated computationally, can be reduced to as little as 50% that of N,N-dimethylacetamide. However, this oc...

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Detalles Bibliográficos
Autores principales: Glover, Stephen A., Rosser, Adam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278557/
https://www.ncbi.nlm.nih.gov/pubmed/30384496
http://dx.doi.org/10.3390/molecules23112834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278557/
https://www.ncbi.nlm.nih.gov/pubmed/30384496
http://dx.doi.org/10.3390/molecules23112834

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