Cargando…

Prediction of GluN2B-CT(1290-1310)/DAPK1 Interaction by Protein–Peptide Docking and Molecular Dynamics Simulation

The interaction of death-associated protein kinase 1 (DAPK1) with the 2B subunit (GluN2B) C-terminus of N-methyl-D-aspartate receptor (NMDAR) plays a critical role in the pathophysiology of depression and is considered a potential target for the structure-based discovery of new antidepressants. Howe...

Descripción completa

Detalles Bibliográficos
Autores principales: Tu, Gao, Fu, Tingting, Yang, Fengyuan, Yao, Lixia, Xue, Weiwei, Zhu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278559/
https://www.ncbi.nlm.nih.gov/pubmed/30463177
http://dx.doi.org/10.3390/molecules23113018