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Prediction of GluN2B-CT(1290-1310)/DAPK1 Interaction by Protein–Peptide Docking and Molecular Dynamics Simulation
The interaction of death-associated protein kinase 1 (DAPK1) with the 2B subunit (GluN2B) C-terminus of N-methyl-D-aspartate receptor (NMDAR) plays a critical role in the pathophysiology of depression and is considered a potential target for the structure-based discovery of new antidepressants. Howe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278559/ https://www.ncbi.nlm.nih.gov/pubmed/30463177 http://dx.doi.org/10.3390/molecules23113018 |