Cargando…

Biomodulatory Treatment With Azacitidine, All-trans Retinoic Acid and Pioglitazone Induces Differentiation of Primary AML Blasts Into Neutrophil Like Cells Capable of ROS Production and Phagocytosis

Effective and tolerable salvage therapies for elderly patients with chemorefractory acute myeloid leukemia (AML) are limited and usually do not change the poor clinical outcome. We recently described in several chemorefractory elderly AML patients that a novel biomodulatory treatment regimen consist...

Descripción completa

Detalles Bibliográficos
Autores principales: Klobuch, Sebastian, Steinberg, Tim, Bruni, Emanuele, Mirbeth, Carina, Heilmeier, Bernhard, Ghibelli, Lina, Herr, Wolfgang, Reichle, Albrecht, Thomas, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278634/
https://www.ncbi.nlm.nih.gov/pubmed/30542286
http://dx.doi.org/10.3389/fphar.2018.01380