Synthesis of Acridines through Alkyne Addition to Diarylamines

A new synthesis of substituted acridines is achieved by palladium-catalyzed addition of terminal acetylenes between the aryl rings of bis(2-bromophenyl)amine. By including a diamine base and elevating the temperature, the reaction pathway favors the formation of acridine over a double Sonogashira re...

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Detalles Bibliográficos
Autores principales: Berger, Kristen E., McCormick, Grant M., Jaye, Joseph A., Rozeske, Christina M., Fort, Eric H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278640/
https://www.ncbi.nlm.nih.gov/pubmed/30400283
http://dx.doi.org/10.3390/molecules23112867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278640/
https://www.ncbi.nlm.nih.gov/pubmed/30400283
http://dx.doi.org/10.3390/molecules23112867

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