Synthetic Evaluation of Standard and Microwave-Assisted Solid Phase Peptide Synthesis of a Long Chimeric Peptide Derived from Four Plasmodium falciparum Proteins

An 82-residue-long chimeric peptide was synthesised by solid phase peptide synthesis (SPPS), following the Fmoc protocol. Microwave (MW) radiation-assisted synthesis was compared to standard synthesis using low loading (0.20 mmol/g) of polyethylene glycol (PEG) resin. Similar synthetic difficulties...

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Detalles Bibliográficos
Autores principales: Varela, Yahson F., Vanegas Murcia, Magnolia, Patarroyo, Manuel Elkin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278645/
https://www.ncbi.nlm.nih.gov/pubmed/30400576
http://dx.doi.org/10.3390/molecules23112877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278645/
https://www.ncbi.nlm.nih.gov/pubmed/30400576
http://dx.doi.org/10.3390/molecules23112877

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