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Efficacy and safety of crizotinib in patients with anaplastic lymphoma kinase-positive advanced-stage non-small-cell lung cancer

INTRODUCTION: Lung cancer is the leading cause of cancer mortality worldwide, despite advances in management, especially with targeted agents and immunotherapy. Numerous oncogenes have been identified that control the growth of these malignancies. Anaplastic lymphoma kinase (ALK) is a tyrosine kinas...

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Detalles Bibliográficos
Autores principales: Mohieldin, Ahmed, Rasmy, Ayman, Ashour, Mohamed, Al-Nassar, Muath, Ali, Rola H, El-Enezi, Fahad G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278708/
https://www.ncbi.nlm.nih.gov/pubmed/30555260
http://dx.doi.org/10.2147/CMAR.S173084