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Inhibition of EZH2 and EGFR produces a synergistic effect on cell apoptosis by increasing autophagy in gastric cancer cells

BACKGROUND: Numerous reports have shown that a combination of two or more drugs leads to better cancer treatment. Inhibitors of zeste homology 2 and epidermal growth factor receptor have been widely used in cancer treatments. However, the mechanisms of the combined use of these two drugs remain elus...

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Detalles Bibliográficos
Autores principales: Yang, Youping, Zhu, Feng, Wang, Qingmei, Ding, Yan, Ying, Rongbiao, Zeng, Linghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278712/
https://www.ncbi.nlm.nih.gov/pubmed/30555238
http://dx.doi.org/10.2147/OTT.S186498