Cargando…
Inhibition of EZH2 and EGFR produces a synergistic effect on cell apoptosis by increasing autophagy in gastric cancer cells
BACKGROUND: Numerous reports have shown that a combination of two or more drugs leads to better cancer treatment. Inhibitors of zeste homology 2 and epidermal growth factor receptor have been widely used in cancer treatments. However, the mechanisms of the combined use of these two drugs remain elus...
Autores principales: | Yang, Youping, Zhu, Feng, Wang, Qingmei, Ding, Yan, Ying, Rongbiao, Zeng, Linghui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278712/ https://www.ncbi.nlm.nih.gov/pubmed/30555238 http://dx.doi.org/10.2147/OTT.S186498 |
Ejemplares similares
-
Diosgenin and GSK126 Produce Synergistic Effects on Epithelial–Mesenchymal Transition in Gastric Cancer Cells by Mediating EZH2 via the Rho/ROCK Signaling Pathway
por: Liu, Shanshan, et al.
Publicado: (2020) -
EGFR-Targeted Hybrid Plasmonic Magnetic Nanoparticles Synergistically Induce Autophagy and Apoptosis in Non-Small Cell Lung Cancer Cells
por: Yokoyama, Tomohisa, et al.
Publicado: (2011) -
Apigenin Induces Autophagy and Cell Death by Targeting EZH2 under Hypoxia Conditions in Gastric Cancer Cells
por: Kim, Tae Woo, et al.
Publicado: (2021) -
Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer Cells
por: Yao, Yizhou, et al.
Publicado: (2016) -
Melatonin in Combination with Albendazole or Albendazole Sulfoxide Produces a Synergistic Cytotoxicity against Malignant Glioma Cells through Autophagy and Apoptosis
por: Hernández-Cerón, Miguel, et al.
Publicado: (2023)