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Overexpression of Mst1 reduces gastric cancer cell viability by repressing the AMPK-Sirt3 pathway and activating mitochondrial fission

BACKGROUND AND OBJECTIVE: Mammalian sterile 20-like kinase 1 (Mst1) plays a critical role in regulating cell survival and apoptosis. However, its influence on gastric cancer cell viability is not understood. Our study aims to explore the specific role of Mst1 in gastric cancer. MATERIALS AND METHODS...

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Detalles Bibliográficos
Autores principales: Yao, Shiwei, Yan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278716/
https://www.ncbi.nlm.nih.gov/pubmed/30555239
http://dx.doi.org/10.2147/OTT.S180851