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Activation of polymeric nanoparticle intracellular targeting overcomes chemodrug resistance in human primary patient breast cancer cells

BACKGROUND: Successfully overcoming obstacles due to anticancer drugs’ toxicity and achieving effective treatment using unique nanotechnology is challenging. The complex nature of breast tumors is mainly due to chemoresistance. Successful docetaxel (DTX) delivery by nanoparticles (NPs) through inhib...

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Detalles Bibliográficos
Autores principales: Abou-El-Naga, Amoura M, Mutawa, Ghada, El-Sherbiny, Ibrahim M, Mousa, Shaker A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278841/
https://www.ncbi.nlm.nih.gov/pubmed/30555232
http://dx.doi.org/10.2147/IJN.S182184