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Pseudogenes Provide Evolutionary Evidence for the Competitive Endogenous RNA Hypothesis

The competitive endogenous RNA (ceRNA) hypothesis is an attractively simple model to explain the biological role of many putatively functionless noncoding RNAs. Under this model, there exist transcripts in the cell whose role is to titrate out microRNAs such that the expression level of another targ...

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Detalles Bibliográficos
Autores principales: Glenfield, Cian, McLysaght, Aoife
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278865/
https://www.ncbi.nlm.nih.gov/pubmed/30252115
http://dx.doi.org/10.1093/molbev/msy183