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MitoNeoD: A Mitochondria-Targeted Superoxide Probe

Mitochondrial superoxide (O(2)(⋅−)) underlies much oxidative damage and redox signaling. Fluorescent probes can detect O(2)(⋅−), but are of limited applicability in vivo, while in cells their usefulness is constrained by side reactions and DNA intercalation. To overcome these limitations, we develop...

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Detalles Bibliográficos
Autores principales: Shchepinova, Maria M., Cairns, Andrew G., Prime, Tracy A., Logan, Angela, James, Andrew M., Hall, Andrew R., Vidoni, Sara, Arndt, Sabine, Caldwell, Stuart T., Prag, Hiran A., Pell, Victoria R., Krieg, Thomas, Mulvey, John F., Yadav, Pooja, Cobley, James N., Bright, Thomas P., Senn, Hans M., Anderson, Robert F., Murphy, Michael P., Hartley, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278870/
https://www.ncbi.nlm.nih.gov/pubmed/28890317
http://dx.doi.org/10.1016/j.chembiol.2017.08.003