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MitoNeoD: A Mitochondria-Targeted Superoxide Probe
Mitochondrial superoxide (O(2)(⋅−)) underlies much oxidative damage and redox signaling. Fluorescent probes can detect O(2)(⋅−), but are of limited applicability in vivo, while in cells their usefulness is constrained by side reactions and DNA intercalation. To overcome these limitations, we develop...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278870/ https://www.ncbi.nlm.nih.gov/pubmed/28890317 http://dx.doi.org/10.1016/j.chembiol.2017.08.003 |