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CSF concentrations of soluble TREM2 as a marker of microglial activation in HIV-1 infection

OBJECTIVE: To explore changes in CSF sTREM2 concentrations in the evolving course of HIV-1 infection. METHODS: In this retrospective cross-sectional study, we measured concentrations of the macrophage/microglial activation marker sTREM2 in CSF samples from 121 HIV-1–infected adults and 11 HIV-negati...

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Detalles Bibliográficos
Autores principales: Gisslén, Magnus, Heslegrave, Amanda, Veleva, Elena, Yilmaz, Aylin, Andersson, Lars-Magnus, Hagberg, Lars, Spudich, Serena, Fuchs, Dietmar, Price, Richard W., Zetterberg, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278890/
https://www.ncbi.nlm.nih.gov/pubmed/30568991
http://dx.doi.org/10.1212/NXI.0000000000000512