Cargando…

CSF concentrations of soluble TREM2 as a marker of microglial activation in HIV-1 infection

OBJECTIVE: To explore changes in CSF sTREM2 concentrations in the evolving course of HIV-1 infection. METHODS: In this retrospective cross-sectional study, we measured concentrations of the macrophage/microglial activation marker sTREM2 in CSF samples from 121 HIV-1–infected adults and 11 HIV-negati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gisslén, Magnus, Heslegrave, Amanda, Veleva, Elena, Yilmaz, Aylin, Andersson, Lars-Magnus, Hagberg, Lars, Spudich, Serena, Fuchs, Dietmar, Price, Richard W., Zetterberg, Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278890/ https://www.ncbi.nlm.nih.gov/pubmed/30568991 http://dx.doi.org/10.1212/NXI.0000000000000512

Ejemplares similares

Herpes zoster in HIV-1 infection: The role of CSF pleocytosis in secondary CSF escape and discordance
por: Hagberg, Lars, et al.
Publicado: (2020)

Cerebrospinal Fluid (CSF) Neuronal Biomarkers across the Spectrum of HIV Infection: Hierarchy of Injury and Detection
por: Peterson, Julia, et al.
Publicado: (2014)

Cerebrospinal Fluid Concentrations of the Synaptic Marker Neurogranin in Neuro-HIV and Other Neurological Disorders
por: Yilmaz, Aylin, et al.
Publicado: (2019)

Cerebrospinal fluid neopterin decay characteristics after initiation of antiretroviral therapy
por: Yilmaz, Aylin, et al.
Publicado: (2013)

Approach to Cerebrospinal Fluid (CSF) Biomarker Discovery and Evaluation in HIV Infection
por: Price, Richard W., et al.
Publicado: (2013)

Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study
por: Gisslén, Magnus, et al.
Publicado: (2015)

Corrigendum to: “Plasma concentration of the neurofilament light protein (NFL) is a biomarker of CNS injury in HIV infection: A cross-sectional study” [EBioMedicine 3 (216) 135–140]
por: Gisslén, Magnus, et al.
Publicado: (2016)

Association between Plasma Homocysteine Levels and Neuronal Injury in HIV Infection
por: Ahlgren, Erika, et al.
Publicado: (2016)

Blood–brain barrier integrity, intrathecal immunoactivation, and neuronal injury in HIV
por: Anesten, Birgitta, et al.
Publicado: (2016)

Cerebrospinal fluid viral breakthrough in two HIV-infected subjects on darunavir/ritonavir monotherapy
por: Gisslén, Magnus, et al.
Publicado: (2012)

Cerebrospinal fluid levels of glial marker YKL-40 strongly associated with axonal injury in HIV infection
por: Hermansson, Linn, et al.
Publicado: (2019)

Cerebrospinal fluid HIV-1 RNA, intrathecal immunoactivation, and drug concentrations after treatment with a combination of saquinavir, nelfinavir, and two nucleoside analogues: the M61022 study
por: Yilmaz, Aylin, et al.
Publicado: (2006)

The effect of vitamin B supplementation on neuronal injury in people living with HIV: a randomized controlled trial
por: Tyrberg, Erika, et al.
Publicado: (2022)

Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection
por: Hagberg, Lars, et al.
Publicado: (2010)

Normalisation of cerebrospinal fluid biomarkers parallels improvement of neurological symptoms following HAART in HIV dementia – case report
por: Andersson, Lars-Magnus, et al.
Publicado: (2006)

Cohort profile: a longitudinal study of HIV infection in the central nervous system with focus on cerebrospinal fluid – the Gothenburg HIV CSF Study Cohort
por: Hagberg, Lars, et al.
Publicado: (2023)

Soluble CD14 in cerebrospinal fluid is associated with markers of inflammation and axonal damage in untreated HIV-infected patients: a retrospective cross-sectional study
por: Jespersen, Sofie, et al.
Publicado: (2016)

Biomarker Evidence of Axonal Injury in Neuroasymptomatic HIV-1 Patients
por: Jessen Krut, Jan, et al.
Publicado: (2014)

Raltegravir Cerebrospinal Fluid Concentrations in HIV-1 Infection
por: Yilmaz, Aylin, et al.
Publicado: (2009)

Residual Central Nervous System Immune Activation Is Not Prevented by Antiretroviral Therapy Initiated During Early Chronic HIV Infection
por: Edén, Arvid, et al.
Publicado: (2023)

Blood biomarkers for HIV infection with focus on neurologic complications—A review
por: Hagberg, Lars, et al.
Publicado: (2022)

Amyloid and tau cerebrospinal fluid biomarkers in HIV infection
por: Gisslén, Magnus, et al.
Publicado: (2009)

Effect of antiretroviral treatment on blood-brain barrier integrity in HIV-1 infection
por: Anesten, Birgitta, et al.
Publicado: (2021)

Correction: Effect of antiretroviral treatment on blood-brain barrier integrity in HIV-1 infection
por: Anesten, Birgitta, et al.
Publicado: (2022)

Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease
por: Heslegrave, Amanda, et al.
Publicado: (2016)

Cerebrospinal Fluid Viral Load and Intrathecal Immune Activation in Individuals Infected with Different HIV-1 Genetic Subtypes
por: Abdulle, Sahra, et al.
Publicado: (2008)

Progressive increase in central nervous system immune activation in untreated primary HIV-1 infection
por: Suh, Joome, et al.
Publicado: (2014)

Proteomic blood profiling in mild, severe and critical COVID-19 patients
por: Patel, Hamel, et al.
Publicado: (2021)

Increased CSF Soluble TREM2 Concentration in Patients With Neurosyphilis
por: Li, Wurong, et al.
Publicado: (2020)

Compartmentalization of cerebrospinal fluid inflammation across the spectrum of untreated HIV-1 infection, central nervous system injury and viral suppression
por: Gisslen, Magnus, et al.
Publicado: (2021)

Plasma levels of soluble TREM2 and neurofilament light chain in TREM2 rare variant carriers
por: Ashton, Nicholas J., et al.
Publicado: (2019)

CSF sTREM2 in delirium—relation to Alzheimer’s disease CSF biomarkers Aβ42, t-tau and p-tau
por: Henjum, Kristi, et al.
Publicado: (2018)

Serum neopterin levels in relation to mild and severe COVID-19
por: Robertson, Josefina, et al.
Publicado: (2020)

Soluble TREM2 induces inflammatory responses and enhances microglial survival
por: Zhong, Li, et al.
Publicado: (2017)

Cerebrospinal fluid signs of neuronal damage after antiretroviral treatment interruption in HIV-1 infection
por: Gisslén, Magnus, et al.
Publicado: (2005)

Plasma concentration of neurofilament light chain protein decreases after switching from tenofovir disoproxil fumarate to tenofovir alafenamide fumarate
por: Hermansson, Linn, et al.
Publicado: (2019)

Viral Antigen and Inflammatory Biomarkers in Cerebrospinal Fluid in Patients With COVID-19 Infection and Neurologic Symptoms Compared With Control Participants Without Infection or Neurologic Symptoms
por: Edén, Arvid, et al.
Publicado: (2022)

Lyme neuroborreliosis in HIV-1 positive men successfully treated with oral doxycycline: a case series and literature review
por: Bremell, Daniel, et al.
Publicado: (2011)

Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup
por: Woollacott, Ione O. C., et al.
Publicado: (2018)

African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants
por: Schindler, Suzanne E., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_agiq9qti67sfgrds1p2a4g7vdd