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A phase II/III randomized, multicenter trial of prednisone/sirolimus versus prednisone/ sirolimus/calcineurin inhibitor for the treatment of chronic graft-versus-host disease: BMT CTN 0801

Initial therapy of chronic graft-versus-host disease is prednisone ± a calcineurin-inhibitor, but most patients respond inadequately. In a randomized, adaptive, phase II/III, multicenter trial we studied whether prednisone/sirolimus or prednisone/sirolimus/photopheresis was more effective than predn...

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Detalles Bibliográficos
Autores principales: Carpenter, Paul A., Logan, Brent R., Lee, Stephanie J., Weisdorf, Daniel J., Johnston, Laura, Costa, Luciano J., Kitko, Carrie L., Bolaños-Meade, Javier, Sarantopoulos, Stefanie, Alousi, Amin M., Abhyankar, Sunil, Waller, Edmund K., Mendizabal, Adam, Zhu, Jiaxi, O’Brien, Kelly A., Lazaryan, Aleksandr, Wu, Juan, Nemecek, Eneida R., Pavletic, Steven Z., Cutler, Corey S., Horowitz, Mary M., Arora, Mukta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278959/
https://www.ncbi.nlm.nih.gov/pubmed/29954931
http://dx.doi.org/10.3324/haematol.2018.195123