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Somatic mutation-associated T follicular helper cell elevation in lung adenocarcinoma
T follicular helper cells (Tfh) play crucial roles in the development of humoral immunity. In the B cell-rich germinal center of lymphoid organs, they select for high-affinity B cells and aid in their maturation. While Tfh have known roles in B cell malignancies and have prognostic value in some epi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279324/ https://www.ncbi.nlm.nih.gov/pubmed/30524903 http://dx.doi.org/10.1080/2162402X.2018.1504728 |