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ppargc1a controls nephron segmentation during zebrafish embryonic kidney ontogeny

Nephron segmentation involves a concert of genetic and molecular signals that are not fully understood. Through a chemical screen, we discovered that alteration of peroxisome proliferator-activated receptor (PPAR) signaling disrupts nephron segmentation in the zebrafish embryonic kidney (Poureetezad...

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Detalles Bibliográficos
Autores principales: Chambers, Joseph M, Poureetezadi, Shahram Jevin, Addiego, Amanda, Lahne, Manuela, Wingert, Rebecca A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279350/
https://www.ncbi.nlm.nih.gov/pubmed/30475208
http://dx.doi.org/10.7554/eLife.40266