Fragile X mental retardation protein is a Zika virus restriction factor that is antagonized by subgenomic flaviviral RNA

Subgenomic flaviviral RNA (sfRNA) accumulates during infection due to incomplete degradation of viral genomes and interacts with cellular proteins to promote infection. Here we identify host proteins that bind the Zika virus (ZIKV) sfRNA. We identified fragile X mental retardation protein (FMRP) as...

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Detalles Bibliográficos
Autores principales: Soto-Acosta, Ruben, Xie, Xuping, Shan, Chao, Baker, Coleman K, Shi, Pei-Yong, Rossi, Shannan L, Garcia-Blanco, Mariano A, Bradrick, Shelton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279352/
https://www.ncbi.nlm.nih.gov/pubmed/30511641
http://dx.doi.org/10.7554/eLife.39023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279352/
https://www.ncbi.nlm.nih.gov/pubmed/30511641
http://dx.doi.org/10.7554/eLife.39023

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