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The S6 gate in regulatory Kv6 subunits restricts heteromeric K(+) channel stoichiometry

The Shaker-like family of voltage-gated K(+) channels comprises four functionally independent gene subfamilies, Shaker (Kv1), Shab (Kv2), Shaw (Kv3), and Shal (Kv4), each of which regulates distinct aspects of neuronal excitability. Subfamily-specific assembly of tetrameric channels is mediated by t...

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Detalles Bibliográficos
Autores principales: Pisupati, Aditya, Mickolajczyk, Keith J., Horton, William, van Rossum, Damian B., Anishkin, Andriy, Chintapalli, Sree V., Li, Xiaofan, Chu-Luo, Jose, Busey, Gregory, Hancock, William O., Jegla, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279357/
https://www.ncbi.nlm.nih.gov/pubmed/30322883
http://dx.doi.org/10.1085/jgp.201812121