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Ion channels can be allosterically regulated by membrane domains near a de-mixing critical point

Ion channels are embedded in the plasma membrane, a compositionally diverse two-dimensional liquid that has the potential to exert profound influence on their function. Recent experiments suggest that this membrane is poised close to an Ising critical point, below which cell-derived plasma membrane...

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Detalles Bibliográficos
Autores principales: Kimchi, Ofer, Veatch, Sarah L., Machta, Benjamin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279359/
https://www.ncbi.nlm.nih.gov/pubmed/30455180
http://dx.doi.org/10.1085/jgp.201711900