Cargando…

Splicing of an automodulatory domain in Ca(v)1.4 Ca(2+) channels confers distinct regulation by calmodulin

Ca(2+) influx through Ca(v)1.4 L-type Ca(2+) channels supports the sustained release of glutamate from photoreceptor synaptic terminals in darkness, a process that is critical for vision. Consistent with this role, Ca(v)1.4 exhibits weak Ca(2+)-dependent inactivation (CDI)—a negative feedback regula...

Descripción completa

Detalles Bibliográficos
Autores principales: Williams, Brittany, Haeseleer, Françoise, Lee, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279360/
https://www.ncbi.nlm.nih.gov/pubmed/30355583
http://dx.doi.org/10.1085/jgp.201812140