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Splicing of an automodulatory domain in Ca(v)1.4 Ca(2+) channels confers distinct regulation by calmodulin
Ca(2+) influx through Ca(v)1.4 L-type Ca(2+) channels supports the sustained release of glutamate from photoreceptor synaptic terminals in darkness, a process that is critical for vision. Consistent with this role, Ca(v)1.4 exhibits weak Ca(2+)-dependent inactivation (CDI)—a negative feedback regula...
Autores principales: | Williams, Brittany, Haeseleer, Françoise, Lee, Amy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279360/ https://www.ncbi.nlm.nih.gov/pubmed/30355583 http://dx.doi.org/10.1085/jgp.201812140 |
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