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The weak voltage dependence of pannexin 1 channels can be tuned by N-terminal modifications

Pannexins are a family of ATP release channels important for physiological and pathological processes like blood pressure regulation, epilepsy, and neuropathic pain. To study these important channels in vitro, voltage stimulation is the most common and convenient tool, particularly for pannexin 1 (P...

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Detalles Bibliográficos
Autores principales: Michalski, Kevin, Henze, Erik, Nguyen, Phillip, Lynch, Patrick, Kawate, Toshimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279361/
https://www.ncbi.nlm.nih.gov/pubmed/30377218
http://dx.doi.org/10.1085/jgp.201711804