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Chromomycin A(2) potently inhibits glucose-stimulated insulin secretion from pancreatic β cells

Modulators of insulin secretion could be used to treat diabetes and as tools to investigate β cell regulatory pathways in order to increase our understanding of pancreatic islet function. Toward this goal, we previously used an insulin-linked luciferase that is cosecreted with insulin in MIN6 β cell...

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Detalles Bibliográficos
Autores principales: Kalwat, Michael A., Hwang, In Hyun, Macho, Jocelyn, Grzemska, Magdalena G., Yang, Jonathan Z., McGlynn, Kathleen, MacMillan, John B., Cobb, Melanie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279362/
https://www.ncbi.nlm.nih.gov/pubmed/30352794
http://dx.doi.org/10.1085/jgp.201812177