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A bilobal model of Ca(2+)-dependent inactivation to probe the physiology of L-type Ca(2+) channels

L-type calcium channels (LTCCs) are critical elements of normal cardiac function, playing a major role in orchestrating cardiac electrical activity and initiating downstream signaling processes. LTCCs thus use feedback mechanisms to precisely control calcium (Ca(2+)) entry into cells. Of these, Ca(2...

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Detalles Bibliográficos
Autores principales: Limpitikul, Worawan B., Greenstein, Joseph L., Yue, David T., Dick, Ivy E., Winslow, Raimond L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279366/
https://www.ncbi.nlm.nih.gov/pubmed/30470716
http://dx.doi.org/10.1085/jgp.201812115