Salmonella SipA mimics a cognate SNARE for host Syntaxin8 to promote fusion with early endosomes

SipA is a major effector of Salmonella, which causes gastroenteritis and enteric fever. Caspase-3 cleaves SipA into two domains: the C-terminal domain regulates actin polymerization, whereas the function of the N terminus is unknown. We show that the cleaved SipA N terminus binds and recruits host S...

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Detalles Bibliográficos
Autores principales: Singh, Pawan Kishor, Kapoor, Anjali, Lomash, Richa Madan, Kumar, Kamal, Kamerkar, Sukrut C., Pucadyil, Thomas J., Mukhopadhyay, Amitabha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279372/
https://www.ncbi.nlm.nih.gov/pubmed/30309979
http://dx.doi.org/10.1083/jcb.201802155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279372/
https://www.ncbi.nlm.nih.gov/pubmed/30309979
http://dx.doi.org/10.1083/jcb.201802155

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