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Salmonella SipA mimics a cognate SNARE for host Syntaxin8 to promote fusion with early endosomes
SipA is a major effector of Salmonella, which causes gastroenteritis and enteric fever. Caspase-3 cleaves SipA into two domains: the C-terminal domain regulates actin polymerization, whereas the function of the N terminus is unknown. We show that the cleaved SipA N terminus binds and recruits host S...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279372/ https://www.ncbi.nlm.nih.gov/pubmed/30309979 http://dx.doi.org/10.1083/jcb.201802155 |