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Structural insight into microtubule stabilization and kinesin inhibition by Tau family MAPs

The Tau family microtubule-associated proteins (MAPs) promote microtubule stabilization and regulate microtubule-based motility. They share the C-terminal microtubule-binding domain, which includes three to five tubulin-binding repeats. Different numbers of repeats formed by alternative splicing hav...

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Detalles Bibliográficos
Autores principales: Shigematsu, Hideki, Imasaki, Tsuyoshi, Doki, Chihiro, Sumi, Takuya, Aoki, Mari, Uchikubo-Kamo, Tomomi, Sakamoto, Ayako, Tokuraku, Kiyotaka, Shirouzu, Mikako, Nitta, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279373/
https://www.ncbi.nlm.nih.gov/pubmed/30275105
http://dx.doi.org/10.1083/jcb.201711182