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Keratin 6 regulates collective keratinocyte migration by altering cell–cell and cell–matrix adhesion

The a and b isoforms of keratin 6 (K6), a type II intermediate filament (IF) protein, are robustly induced upon injury to interfollicular epidermis. We previously showed that complete loss of K6a/K6b stimulates keratinocyte migration, correlating with enhanced Src activity. In this study, we demonst...

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Detalles Bibliográficos
Autores principales: Wang, Fengrong, Chen, Song, Liu, Hans B., Parent, Carole A., Coulombe, Pierre A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279382/
https://www.ncbi.nlm.nih.gov/pubmed/30389720
http://dx.doi.org/10.1083/jcb.201712130