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Differential GAP requirement for Cdc42-GTP polarization during proliferation and sexual reproduction
The formation of a local zone of Cdc42 GTPase activity, which governs cell polarization in many cell types, requires not only local activation but also switch-off mechanisms. In this study, we identify Rga3, a paralog of Rga4, as a novel Cdc42 GTPase-activating protein (GAP) in the fission yeast Sch...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279383/ https://www.ncbi.nlm.nih.gov/pubmed/30279276 http://dx.doi.org/10.1083/jcb.201806016 |