Cargando…

Differential GAP requirement for Cdc42-GTP polarization during proliferation and sexual reproduction

The formation of a local zone of Cdc42 GTPase activity, which governs cell polarization in many cell types, requires not only local activation but also switch-off mechanisms. In this study, we identify Rga3, a paralog of Rga4, as a novel Cdc42 GTPase-activating protein (GAP) in the fission yeast Sch...

Descripción completa

Detalles Bibliográficos
Autores principales: Gallo Castro, Daniela, Martin, Sophie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279383/
https://www.ncbi.nlm.nih.gov/pubmed/30279276
http://dx.doi.org/10.1083/jcb.201806016