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GTP hydrolysis promotes disassembly of the atlastin crossover dimer during ER fusion
Membrane fusion of the ER is catalyzed when atlastin GTPases anchored in opposing membranes dimerize and undergo a crossed over conformational rearrangement that draws the bilayers together. Previous studies have suggested that GTP hydrolysis triggers crossover dimerization, thus directly driving fu...
Autores principales: | Winsor, James, Machi, Ursula, Han, Qixiu, Hackney, David D., Lee, Tina H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279388/ https://www.ncbi.nlm.nih.gov/pubmed/30249723 http://dx.doi.org/10.1083/jcb.201805039 |
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