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Bone marrow–derived fibroblasts are a functionally distinct stromal cell population in breast cancer

Cancer-associated fibroblasts (CAFs) are highly prominent in breast tumors, but their functional heterogeneity and origin are still largely unresolved. We report that bone marrow (BM)–derived mesenchymal stromal cells (MSCs) are recruited to primary breast tumors and to lung metastases and different...

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Detalles Bibliográficos
Autores principales: Raz, Yael, Cohen, Noam, Shani, Ophir, Bell, Rachel E., Novitskiy, Sergey V., Abramovitz, Lilach, Levy, Carmit, Milyavsky, Michael, Leider-Trejo, Leonor, Moses, Harold L., Grisaru, Dan, Erez, Neta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279405/
https://www.ncbi.nlm.nih.gov/pubmed/30470719
http://dx.doi.org/10.1084/jem.20180818