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Dietary DHA amplifies LXA(4) circuits in tissues and lymph node PMN and is protective in immune-driven dry eye disease
Recently identified regulatory PMN control immune-driven dry eye disease (DED) in females by producing the arachidonic acid (ɷ−6)-derived specialized pro-resolving mediator (SPM), LXA(4), in lymph nodes. Dietary ɷ−3 docosahexaenoic acid (DHA) is protective in DED but mechanisms of action remain elus...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279588/ https://www.ncbi.nlm.nih.gov/pubmed/30104626 http://dx.doi.org/10.1038/s41385-018-0070-z |