Identification of rate-limiting enzymes involved in paclitaxel biosynthesis pathway affected by coronatine and methyl-β-cyclodextrin in Taxus baccata L. cell suspension cultures

BACKGROUND: Paclitaxel is a potent antitumor alkaloid widely used for the treatment of several cancer types. This valuable secondary metabolite naturally exists in the inner bark of Taxus species in very low amounts. The small-scale production of paclitaxel in Taxus cell cultures requires utilizatio...

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Detalles Bibliográficos
Autores principales: Kashani, Kimia, Jalali Javaran, Mokhtar, Sabet, Mohammad Sadegh, Moieni, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279667/
https://www.ncbi.nlm.nih.gov/pubmed/30377988
http://dx.doi.org/10.1007/s40199-018-0217-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279667/
https://www.ncbi.nlm.nih.gov/pubmed/30377988
http://dx.doi.org/10.1007/s40199-018-0217-1

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